Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis.

@article{Breuer2005SafetyAE,
  title={Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis.},
  author={Kristine Breuer and Thomas T Werfel and Alexander Kapp},
  journal={American journal of clinical dermatology},
  year={2005},
  volume={6 2},
  pages={65-77}
}
Approximately 10-20% of infants in industrialized countries experience atopic dermatitis. In recent decades topical corticosteroids have been the first-choice therapy for treatment of flares. However, this form of therapy may induce skin atrophy, especially after application to facial lesions or with long-term use. Thus, development of new anti-inflammatory topical agents for the treatment of childhood atopic dermatitis was needed. The topical calcineurin inhibitors tacrolimus and pimecrolimus… CONTINUE READING