Safety and efficacy of regional citrate anticoagulation during 8-hour sustained low-efficiency dialysis.

@article{Clark2008SafetyAE,
  title={Safety and efficacy of regional citrate anticoagulation during 8-hour sustained low-efficiency dialysis.},
  author={John David Clark and Gerald I Schulman and Thomas A. Golper},
  journal={Clinical journal of the American Society of Nephrology : CJASN},
  year={2008},
  volume={3 3},
  pages={736-42}
}
BACKGROUND AND OBJECTIVES Patients who may benefit from sustained low-efficiency dialysis therapy are often at risk for bleeding. A safe and simple "regional" anticoagulation strategy would be beneficial. The modification of existing regional citrate anticoagulation protocols to typically performed 8-h sustained low-efficiency dialysis is necessary. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Sustained low-efficiency dialysis was performed at blood and dialysate rates of 250 and 300 ml/min… CONTINUE READING