Safety and efficacy of pregabalin in patients with central post-stroke pain

  title={Safety and efficacy of pregabalin in patients with central post-stroke pain},
  author={Jong S. Kim and Guy M Bashford and T. Kevin Murphy and Andrew Martin and Raymond Cheung},
Pregabalin has demonstrated efficacy in several forms of neuropathic pain, but its long-term efficacy in central post-stroke pain (CPSP) is unproven. We evaluated the efficacy and safety of pregabalin versus placebo in patients with CPSP. A 13-week, randomized, double-blind, multicenter, placebo-controlled, parallel group study of 150 to 600 mg/day pregabalin was conducted in patients aged ≥18 years with CPSP. The primary efficacy endpoint was the mean pain score on the Daily Pain Rating Scale… CONTINUE READING

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