Safety and efficacy of ibuprofen versus indomethacin in preterm infants

Sir: The study of Lago et al. [1], like all investigations on premature infants, is flawed by the absence of a physiological control group. The authors base their investigation on the false premise that respiratory distress syndrome (RDS) and patent ductus arteriosus (PDA) are natural consequences of premature birth that require treatment. However, there is… CONTINUE READING