Safety and efficacy of early parenteral lipid and high-dose amino acid administration to very low birth weight infants.

@article{Vlaardingerbroek2013SafetyAE,
  title={Safety and efficacy of early parenteral lipid and high-dose amino acid administration to very low birth weight infants.},
  author={Hester Vlaardingerbroek and M J Vermeulen and Denise Rook and Chris H P van den Akker and Kristien Y Dorst and J. L. Darcos Wattimena and Andr{\'a}s Vermes and Henk Schierbeek and Johannes B van Goudoever},
  journal={The Journal of pediatrics},
  year={2013},
  volume={163 3},
  pages={
          638-44.e1-5
        }
}
OBJECTIVE To assess the efficacy and safety of early parenteral lipid and high-dose amino acid (AA) administration from birth onwards in very low birth weight (VLBW, birth weight <1500 g) infants. STUDY DESIGN VLBW infants (n = 144; birth weight 862 ± 218 g; gestational age 27.4 ± 2.2 weeks) were randomized to receive 2.4 g of AA kg(-1) · d(-1) (control group), or 2.4 g AA kg(-1) · d(-1) plus 2-3 g lipids kg(-1) · d(-1) (AA + lipid group), or 3.6 g AA kg(-1) · d(-1) plus 2-3 g lipids kg(-1… CONTINUE READING

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Early total parenteral nutrition in very low birthweight infants: is it safe? Is it worth it?

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