Safety and efficacy of Crotalidae Polyvalent Immune Fab in pediatric crotaline envenomations.

@article{Pizon2007SafetyAE,
  title={Safety and efficacy of Crotalidae Polyvalent Immune Fab in pediatric crotaline envenomations.},
  author={Anthony F. Pizon and Bradley D Riley and Frank Lovecchio and Ruqayya Gill},
  journal={Academic emergency medicine : official journal of the Society for Academic Emergency Medicine},
  year={2007},
  volume={14 4},
  pages={373-6}
}
BACKGROUND Since it was approved by the Food and Drug Administration in October 2000, Crotalidae Polyvalent Immune Fab (CroFab) has largely replaced previously used crotaline antivenom. CroFab is more specifically tailored for crotalids of North America and is less allergenic than whole immunoglobulin antivenoms. However, premarketing and postmarketing studies have excluded children. OBJECTIVES To describe the safety and efficacy of CroFab in pediatric crotaline envenomations. METHODS Using… CONTINUE READING

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