Safety and benefit considerations for menopausal hormone therapy

@article{Pickar2017SafetyAB,
  title={Safety and benefit considerations for menopausal hormone therapy},
  author={James H. Pickar and David F Archer and Risa Kagan and JoAnn V. Pinkerton and Hugh S. Taylor},
  journal={Expert Opinion on Drug Safety},
  year={2017},
  volume={16},
  pages={941 - 954}
}
ABSTRACT Introduction: While benefits and risks of hormone therapy (HT) have been shown in rigorous randomized, controlled trials, clinical use and further study have discovered effects of age, time of HT initiation, and differential effects of various regimens and administration routes on its safety profile. Areas covered: The safety of HT with regard to cardiovascular disease, thrombosis, the endometrium, the breast, and cognition was reviewed. Differential safety effects of estradiol versus… Expand
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