Safety and Tolerability of Increased Rate of Infusion of Intravenous Immunoglobulin G, 10% in Antibody-Deficient Patients

@article{Gelfand2006SafetyAT,
  title={Safety and Tolerability of Increased Rate of Infusion of Intravenous Immunoglobulin G, 10% in Antibody-Deficient Patients},
  author={Erwin W. Gelfand and Kim Hanna},
  journal={Journal of Clinical Immunology},
  year={2006},
  volume={26},
  pages={284-290}
}
The incidence and severity of infusion-related adverse events (AEs) after infusions of IGIV-C, 10%, (Gamunex®) at 0.14 mL/kg/min versus 0.08 mL/kg/min (standard rate) were compared. Patients with confirmed PID received two infusions 3–4 weeks apart with IGIV-C, 10% 400–600 mg/kg. Patients received their first infusion at 0.08 or 0.14 mL/kg/min and their second infusion 3–4 weeks later at the alternate rate, at an established step-wise rate increase. Ninety-seven of 100 patients remained valid… CONTINUE READING