Safety and Immunogenicity Assessment of an Oral Cholera Vaccine through Phase I Clinical Trial in Korea

@inproceedings{Baik2014SafetyAI,
  title={Safety and Immunogenicity Assessment of an Oral Cholera Vaccine through Phase I Clinical Trial in Korea},
  author={Young Ok Baik and Seuk Keun Choi and Jae Woo Kim and Jae Seung Yang and Ick Young Kim and Chan Wha Kim and Jang Hee Hong},
  booktitle={Journal of Korean medical science},
  year={2014}
}
The safety, tolerability and immunogenicity of an oral cholera vaccine (OCV) was assessed in adult Korean male through an open-label, non-comparative clinical study. Two doses of vaccine with an interval of 2 weeks were given to 20 healthy subjects. A total of 7 adverse events occurred in 6 subjects. However, no clinically significant change was observed in electrocardiograms, vital signs, physical examinations, and clinical laboratory tests. The immunogenicity of OCV was evaluated by serum… CONTINUE READING