Safety and Efficacy of Chlorine Dioxide for Legionella Control in a Hospital Water System

  title={Safety and Efficacy of Chlorine Dioxide for Legionella Control in a Hospital Water System},
  author={Zhe Zhang and Carole R. McCann and Janet E. Stout and Steve Piesczynski and Robert Hawks and Radisav D. Vidic and Victor L. Yu},
  journal={Infection Control \&\#x0026; Hospital Epidemiology},
  pages={1009 - 1012}
In a 30-month prospective study, we evaluated the efficacy of chlorine dioxide to control Legionella organisms in a water distribution system of a hospital with 364 patient beds and 74 skilled nursing beds. The number of hot water specimens positive for Legionella organisms decreased from 12 (60%) of 20 to 2 (10%) of 20. An extended time (18 months) was needed to achieve a significant reduction in the rate of Legionella positivity among hot water specimens. At the time of writing, no cases of… 
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Hospital-acquired Legionella infections: an update on the procedures for controlling environmental contamination.
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The implementation and application of a WSP in a hospital, together with the disinfection of the water distribution system with monochloramine, can be effective in controlling the growth of Legionella and in preventing nosocomial Legionella.


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The results indicate that chlorine dioxide may hold promise as a solution to the problem of Legionella contamination of hospital water supplies, as levels of chlorine dioxide and chlorite were below EPA limits.
The Johns Hopkins Hospital in 1999 began to evaluate the safety and efficacy of chlorine dioxide for Legionella control in a potable water system in an acute care hospital environment. The evaluation
keeping Legionella out of water systems
Study of a hospital where three cases of hospital‐acquired Legionnaires' disease were detected in less than two years, chlorine dioxide (ClO2) was considered a cost‐effective approach to disinfection given that ClO2 generators could treat the 23 buildings comprising the hospital complex from one central location.
Experiences of the First 16 Hospitals Using Copper-Silver Ionization for Legionella Control: Implications for the Evaluation of Other Disinfection Modalities
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    Infection Control & Hospital Epidemiology
  • 2003
Copper-silver ionization is now the only disinfection modality to have fulfilled all four evaluation criteria and no cases of hospital-acquired legionnaires' disease have occurred in any hospital since 1995.
Legionella in water distribution systems
Regular culturing of distribution system samples is the key to successful disinfection.
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Test Method: Determination of Inorganic Anions in Drinking Water by Ion Chromatography
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Six years ' experience with chlorine dioxide in control of Legionella pneumophila in potable water supply of Glasgow Royal Infirmary
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