Safety and Efficacy of Caproamin Fides and Tranexamic Acid Versus Placebo in Patients Undergoing Coronary Artery Revascularization

  title={Safety and Efficacy of Caproamin Fides and Tranexamic Acid Versus Placebo in Patients Undergoing Coronary Artery Revascularization},
  author={Alireza Alizadeh Ghavidel and Ziae Totonchi and Mitra Chitsazan and Maziar Gholampour dehaki and Farshid Jalili and Fariborz Farsad and Maral Hejrati},
  journal={Journal of Cardiovascular and Thoracic Research},
  pages={197 - 202}
Introduction: Excessive fibrinolysis contributes to post-cardiopulmonary bypass bleeding. Tranexamic Acid (TXA) and Caproamin Fides are synthetic lysine analogues that inhibit plasminogen-fibrin binding. The present study aimed to compare TXA and Caproamin Fides versus placebo in patients undergoing elective coronary artery revascularization. Methods: We analyzed perioperative data of 300 adult patients undergoing coronary artery revascularization. Patients were randomly allocated to receive… 
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