Safety Evaluation of GX-12. A New DNA Vaccine for HIV Infection in Rodents

@article{Choi2003SafetyEO,
  title={Safety Evaluation of GX-12. A New DNA Vaccine for HIV Infection in Rodents},
  author={Seul Min Choi and Dong Sop Lee and Mi-Kyung Son and Young Sung Sohn and Kyung Koo Kang and Chae -Young Kim and Byung Moon Kim and Won Bae Kim},
  journal={Drug and Chemical Toxicology},
  year={2003},
  volume={26},
  pages={271 - 284}
}
Abstract Toxicity studies for the evaluation of the safety of GX-12, a naked DNA vaccine for the treatment of human immunodeficiency virus (HIV) infection, were performed in rodents. In a single dose intramuscular or intravenous toxicity study, animals were treated with up to 4000 µg/kg of GX-12. During the experimental period, no abnormalities in mortality, clinical finding, or body weight change were observed. For subacute toxicity study, GX-12 was administered intramuscularly once a week for… 

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