Corpus ID: 70693833

Safety Evaluation of BF001, an Anti-diabetic Herbal Preparation in Sprague-Dawley Rats

@inproceedings{Owiredu2011SafetyEO,
  title={Safety Evaluation of BF001, an Anti-diabetic Herbal Preparation in Sprague-Dawley Rats},
  author={W. Owiredu and Takyi N.K. and Okine L.K.N. and S. A.A. and N. Amidu and B. K.A. and S. Antwi and K. Donkor and O. Addai-Mensah},
  year={2011}
}
Background : "BF001" is a herbal preparation made from the leaves of Bridelia ferruginea. Despite its prolonged use in treating diabetes mellitus, there is no empirical evidence of its safety as a hypoglycaemic agent. Objectives : This study evaluated the acute and chronic toxicity of 'BF001' with the view to determining the LD50 and toxic effects on specific organs after prolonged administration in male Spraque-Dawley rats. -1 Methods : Acute toxicity was carried out within 14 days; a single… Expand