Safety, tolerability and pharmacokinetics of udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects.

@article{Kim2008SafetyTA,
  title={Safety, tolerability and pharmacokinetics of udenafil, a novel PDE-5 inhibitor, in healthy young Korean subjects.},
  author={Bo-Hyung Kim and Hyeong-Seok Lim and Jae-yong Chung and Jung-Ryul Kim and Kyoung Soo Lim and Daniel Dungan Sohn and Joo Youn Cho and Kyung-Sang Yu and Seong Gwan Shin and J-S. Paick and Ik-kyuk Jang},
  journal={British journal of clinical pharmacology},
  year={2008},
  volume={65 6},
  pages={
          848-54
        }
}
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT The phosphodiesterase (PDE) type 5 inhibitor is a widely used agent that facilitates penile erection. Udenafil is newly developed as a PDE-5 inhibitor. WHAT THIS STUDY ADDS This is the first study to determine the safety, tolerability and pharmacokinetics of udenafil in healthy subjects. Udenafil was safe and well tolerated in healthy Korean subjects. The AUC and C(max) of udenafil increased supraproportionally with increasing dose upon single… CONTINUE READING
BETA

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 35 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 19 REFERENCES

Similar Papers

Loading similar papers…