Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial

@article{Zhang2020SafetyTA,
  title={Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial},
  author={Yanjun Zhang and Gang Zeng and Hongxing Pan and Changgui Li and Yaling Hu and Kai Chu and Weixiao Han and Zhen Chen and Rong Tang and Weidong Yin and Xin Chen and Yuansheng Hu and Xiaoyong Liu and Congbing Jiang and Jing-xin Li and Minnan Yang and Yan Song and Xiangxi Wang and Qiang Gao and Fengcai Zhu},
  journal={The Lancet. Infectious Diseases},
  year={2020},
  volume={21},
  pages={181 - 192}
}
  • Yanjun Zhang, G. Zeng, +17 authors Fengcai Zhu
  • Published 17 November 2020
  • Medicine
  • The Lancet. Infectious Diseases
Background With the unprecedented morbidity and mortality associated with the COVID-19 pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac (Sinovac Life Sciences, Beijing, China), an inactivated vaccine candidate against COVID-19, containing inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), for its safety, tolerability and immunogenicity. Methods In this randomised, double-blind, placebo-controlled, phase 1/2 clinical trial, healthy… Expand

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