Safety, efficacy, and dosing requirements of bivalirudin in patients with heparin-induced thrombocytopenia.

@article{Kiser2008SafetyEA,
  title={Safety, efficacy, and dosing requirements of bivalirudin in patients with heparin-induced thrombocytopenia.},
  author={Tyree H Kiser and Jessica C Burch and Patrick M Klem and Kathryn L Hassell},
  journal={Pharmacotherapy},
  year={2008},
  volume={28 9},
  pages={1115-24}
}
STUDY OBJECTIVE To evaluate the safety, efficacy, and dosing requirements of bivalirudin in patients with heparin-induced thrombocytopenia (HIT). DESIGN Retrospective cohort study. SETTING University-affiliated hospital. PATIENTS Thirty-seven adults with a diagnosis or history of HIT who were treated with bivalirudin between January 1, 2004, and March 31, 2007. MEASUREMENTS AND MAIN RESULTS Patients had a mean +/- SD age of 50 +/- 16 years and weighed 80 +/- 20 kg; 62% were male, 73… CONTINUE READING

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