Safeguarding nonhuman primate iPS cells with suicide genes.

@article{Zhong2011SafeguardingNP,
  title={Safeguarding nonhuman primate iPS cells with suicide genes.},
  author={Bonan Zhong and Korashon Lynn Watts and Jennifer L. Gori and Martin Wohlfahrt and Joerg Enssle and Jennifer E Adair and Hans-Peter Kiem},
  journal={Molecular therapy : the journal of the American Society of Gene Therapy},
  year={2011},
  volume={19 9},
  pages={1667-75}
}
The development of technology to generate induced pluripotent stem (iPS) cells constitutes one of the most exciting scientific breakthroughs because of the enormous potential for regenerative medicine. However, the safety of iPS cell-related products is a major concern for clinical translation. Insertional mutagenesis, possible oncogenic transformation of… CONTINUE READING