Safe use of brain natriuretic protein to rule out the diagnosis of heart failure depends on the selection of cut off value.

@article{Williams2005SafeUO,
  title={Safe use of brain natriuretic protein to rule out the diagnosis of heart failure depends on the selection of cut off value.},
  author={Simon J Williams and Leong Loke Ng and Russell J O'brien and D P Barker and Y Li and L. B. Tan},
  journal={Heart},
  year={2005},
  volume={91 8},
  pages={1090-1}
}
T he recently published National Institute for Clinical Excellence (NICE) chronic heart failure (CHF) guideline has recommended the use of brain natriuretic peptide (BNP) to help rule out the diagnosis of CHF, and quoted a sensitivity of 90–97%. Moreover, for purposes of medical audit, patients previously labelled as having CHF, but without a confirmation… CONTINUE READING