Safe amounts of contrast medium for angiocardiography in neonates and infants.


The results were analysed of 485 (biplane) cineangiocardiograms performed in 200 consecutive cardiac investigations on neonates (under 4 wk) and infants (4 wk to 1 yr). 10 deaths occurred during or within 24 h of cardiac catheterization, all in patients who were profoundly acidemic because of their hemodynamic disturbance. A total dose of Cardio-Conray at any one investigation of 4-5 ml/kg body weight was satisfactory and without undue risk. Single injections of 1.5-2.0 ml/kg body weight were safe whilst providing optimal diagnostic information. The interval between multiple injections did not appear to affect the risk to the patients.


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@article{Fox1977SafeAO, title={Safe amounts of contrast medium for angiocardiography in neonates and infants.}, author={Kim M. Fox and Ruby G Patel and Marco Bonvicini and Joanne Taylor and G R Graham}, journal={European journal of cardiology}, year={1977}, volume={5 5}, pages={373-80} }