Saddle nose deformity and septal perforation in granulomatosis with polyangiitis

@article{Coordes2018SaddleND,
  title={Saddle nose deformity and septal perforation in granulomatosis with polyangiitis},
  author={Annekatrin Coordes and Suzanne M. Loose and VM. Hofmann and Grant S. Hamilton and Frank Riedel and Dirk Jan Menger and Andreas E Albers},
  journal={Clinical Otolaryngology},
  year={2018},
  volume={43},
  pages={291 - 299}
}
Patients who have granulomatosis with polyangiitis (GPA, syn. M. Wegener) often develop an external nose deformity which may have devastating psychological effects. Therefore, reconstruction of nasal deformities by rhinoplasty may become necessary to achieve a normal appearance. 
12 Citations
Correction of the Saddle Nose Deformity.
TLDR
Reconstructing the septum is a necessary prerequisite to correcting the contour of the nose, and patients suffering from disfiguring saddle noses can be safely operated on-even those with vasculitic diseases.
ENT manifestations of Granulomatosis with polyangiitis
Ear, nose, and throat (ENT) symptoms represent the most frequent manifestations at the onset of granulomatosis with polyangiitis (GPA). The diagnosis of the localized form of GPA remains challenging
Localized Granulomatous with Polyangiitis (GPA): Varied Clinical Presentations and Update on Treatment
TLDR
This is a narrative review that provides a comprehensive overview of localized granulomatosis with polyangiitis and current treatment options.
Grafting Techniques in Primary and Revision Rhinoplasty.
TLDR
A case approach is provided focused on the use of structural grafting in rhinoplasty, as surgical procedures have become more technically complex and the type of grafts use for both primary and secondary rh inoplasty have undergone significant evolution.
Nasal Septal Perforation Closure by "Sandwich Grafts": Technique, Initial Results.
TLDR
The authors have identified a reliable technique closing septal perforations by an autologous "sandwich graft" layered around a piece of auricular cartilage, covered with temporal fascia, thus emulating the physiological layers of the nasal septum.
Refinements in Saddle Nose Reconstruction
TLDR
The authors propose their own classification system for saddle nose with one new category and several approaches to deal with this condition in accordance with the level of severity, and strongly advocate major septal reconstruction for most cases of saddle nose.
The role of surgery in antineutrophil cytoplasmic antibody–associated vasculitides affecting the nose and sinuses: A systematic review
TLDR
Surgical intervention during the active phase of ANCA–associated vasculitis disease can improve the patient’s symptoms and enable histological diagnosis, and provide symptom relief and nasal reconstructive surgery consideration when in remission.
Patologia del setto nasale (deviazione del setto esclusa)
Riassunto Il setto nasale, situato al centro delle fosse nasali, e ormai visibile nella sua interezza grazie all’esame obiettivo in nasofibroscopia. Costituito da una porzione cartilaginea anteriore
Patología del tabique nasal (a excepción de la desviación septal)
Resumen El tabique nasal, situado en el centro de las fosas nasales, se puede visualizar actualmente en su totalidad gracias a la exploracion fisica con nasofibroendoscopia. Esta constituido por una
Wegener’s
...
1
2
...

References

SHOWING 1-10 OF 45 REFERENCES
Repair of saddle nose deformity in Wegener's granulomatosis and ectodermal dysplasia.
TLDR
By extranasal incisions the nasal dorsum has been successfully reconstructed by transplanting autogenic conchal cartilage and there has been no resorption or displacement of the transplant after twelve months in the case of ectodermal dysplasia, and after 25 years in the patient with Wegener's granulomatosis despite a severe recurrence of this disease.
Restylane--a temporary alternative for saddle nose deformity in nasal Wegener's granulomatosis--how we do it.
We present a case of a 22-year-old female with nasal collapse secondary to Wegener's Granulomatosis who has benefited from Restylane® injection use to improve cosmesis whilst awaiting formal nasal
[Chronic rhinosinusitis with septal perforation. Differential diagnostic considerations].
TLDR
The otolaryngologist's role is to initiate, in close cooperation with a rheumatologist, therapy with sulfatrimethoprim, as well as with immunosuppressants if necessary, which helps stabilize the symptomatology and may prevent progressive systemic disease.
Long‐Term Follow‐up of Repair of External Nasal Deformities in Patients With Wegener's Granulomatosis
TLDR
The study was initiated to determine the efficacy and safety of reconstructing external nasal deformities in patients with Wegener's granulomatosis, characterized histologically by necrotizing granulomas and vasculitis.
Reconstruction of Nasal Deformity in Wegener’s Granulomatosis: Contraindication or Benefit?
TLDR
External nasal reconstruction for patients affected by WG appears to be safe and effective if the disease is in remission before any operation, and high-dose immune suppression therapy could not be observed in the patients of this series, all of whom were receiving immunosuppressive medication.
Sinonasal Wegener granulomatosis: A single‐institution experience with 120 cases
TLDR
The objectives of the study were to describe sinonasal symptoms and signs at the time of initial otolaryngologic evaluation, and to review indications and outcomes for rhinologic surgery in WG at the authors' institution.
Reconstruction of short nose deformity using nasolabial flaps pedicled on the infraorbital vessels.
Bilateral nasolabial flaps pedicled on the infraorbital vessels, and costal cartilage grafts were used to reconstruct a severe nasal deformity caused by Wegener's granuloma. We believe this flap is
Nasal manifestations of granulomatous disease.
TLDR
The most common infectious and non-infectious conditions and their clinical features are described.
Detailed analysis of graft techniques for nasal reconstruction following Wegener granulomatosis.
TLDR
With a multidisciplinary team approach to pre- and postoperative patient management and careful surgical technique, reliable and excellent functional and cosmetic outcomes can be achieved with costal cartilage grafts.
Considerations in the etiology, treatment, and repair of septal perforations.
  • R. Kridel
  • Medicine
    Facial plastic surgery clinics of North America
  • 2004
TLDR
Presenting symptoms and findings for septal perforations, the history and physical examination, causes, helpful hints for prevention of perforation, and surgical and nonsurgical treatment options and outcomes are described.
...
1
2
3
4
5
...