SadA, a trimeric autotransporter from Salmonella enterica serovar Typhimurium, can promote biofilm formation and provides limited protection against infection.

@article{Raghunathan2011SadAAT,
  title={SadA, a trimeric autotransporter from Salmonella enterica serovar Typhimurium, can promote biofilm formation and provides limited protection against infection.},
  author={Dhaarini Raghunathan and Timothy J. Wells and Faye C Morris and Robert K. Shaw and Saeeda Bobat and Sarah E. Peters and G. Keppie Paterson and Karina Tveen Jensen and Denisse L. Leyton and Jessica M A Blair and Douglas F Browning and John Pravin and Adriana Flores-Langarica and Jessica R. Hitchcock and Claudia T. P. Moraes and Roxane Maria Fontes Piazza and Duncan J Maskell and Mark Alexander Webber and Robin C May and Calman A MacLennan and Laura J V Piddock and Adam F Cunningham and Ian R. Henderson},
  journal={Infection and immunity},
  year={2011},
  volume={79 11},
  pages={4342-52}
}
Salmonella enterica is a major cause of morbidity worldwide and mortality in children and immunocompromised individuals in sub-Saharan Africa. Outer membrane proteins of Salmonella are of significance because they are at the interface between the pathogen and the host, they can contribute to adherence, colonization, and virulence, and they are frequently targets of antibody-mediated immunity. In this study, the properties of SadA, a purported trimeric autotransporter adhesin of Salmonella… CONTINUE READING
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