Saccharomyces cerevisiae Pip2p-Oaf1p regulates PEX25 transcription through an adenine-less ORE.

@article{Rottensteiner2003SaccharomycesCP,
  title={Saccharomyces cerevisiae Pip2p-Oaf1p regulates PEX25 transcription through an adenine-less ORE.},
  author={Hanspeter Rottensteiner and Andreas Hartig and Barbara Hamilton and H J L A Ruis and Ralf Erdmann and Aner Gurvitz},
  journal={European journal of biochemistry},
  year={2003},
  volume={270 9},
  pages={2013-22}
}
The role of the Saccharomyces cerevisiae Pip2p-Oaf1p transcription factor was examined in reference to the regulation of the peroxin gene PEX25 involved in peroxisome proliferation. The PEX25 promoter contains an oleate response element (ORE)-like sequence comprising a CGG palindrome lacking a canonical adenine, which is considered critical for element function and Pip2p-Oaf1p binding. Pex25p levels were higher in wild-type cells grown on oleic acid medium than in those grown on ethanol, but… CONTINUE READING