Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA.

@article{Alani1997SaccharomycesCM,
  title={Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA.},
  author={Eric Alani and Seung-Hyun Lee and Michael F. Kane and James C Griffith and Richard D Kolodner},
  journal={Journal of molecular biology},
  year={1997},
  volume={265 3},
  pages={289-301}
}
Genetic and biochemical studies have suggested that mismatch repair proteins interact with recombination intermediates to prevent recombination, or to limit the extent of formation of heteroduplex DNA during recombination between divergent DNA sequences. To test the idea that mismatch repair proteins regulate recombination by interacting with recombination intermediates, we investigated whether the Saccharomyces cerevisiae MutS homolog MSH2 could interact with Holliday junctions. Both filter… CONTINUE READING

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