Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion.

Abstract

CTF4 and CTF18 are required for high-fidelity chromosome segregation. Both exhibit genetic and physical ties to replication fork constituents. We find that absence of either CTF4 or CTF18 causes sister chromatid cohesion failure and leads to a preanaphase accumulation of cells that depends on the spindle assembly checkpoint. The physical and genetic… (More)

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Cite this paper

@article{Hanna2001SaccharomycesCC, title={Saccharomyces cerevisiae CTF18 and CTF4 are required for sister chromatid cohesion.}, author={Jackie Hanna and Elke Kroll and Victoria Lundblad and Fred Spencer}, journal={Molecular and cellular biology}, year={2001}, volume={21 9}, pages={3144-58} }