Saccades in presymptomatic and early stages of Huntington disease.

  title={Saccades in presymptomatic and early stages of Huntington disease.},
  author={Tanya M Blekher and Shannon A Johnson and Jeanine Marshall and Keith D. White and S Hui and Michael T. Weaver and Jennifer Gray and Reynold Yee and Julie C. Stout and Xabier Beristain and Joanne M Wojcieszek and Tatiana Foroud},
  volume={67 3},
OBJECTIVE To evaluate quantitative measures of eye movements as possible biomarkers in prediagnostic and early stages of Huntington disease (HD). METHODS The study sample (n = 215) included individuals both at risk and recently diagnosed with HD. All participants completed a uniform clinical evaluation which included administration of the Unified Huntington's Disease Rating Scale (UHDRS) by a movement disorder neurologist and molecular testing to determine HD gene status. A high resolution… CONTINUE READING
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The neurology of eye movements

  • RJ Leigh, DS Zee
  • 1999

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