Saccades in presymptomatic and early stages of Huntington disease

  title={Saccades in presymptomatic and early stages of Huntington disease},
  author={T. Blekher and S. A. Johnson and Jeanine Marshall and K. White and S. Hui and M. Weaver and J. Gray and R. Yee and J. Stout and X. Beristain and J. Wojcieszek and T. Foroud},
  pages={394 - 399}
  • T. Blekher, S. A. Johnson, +9 authors T. Foroud
  • Published 2006
  • Medicine
  • Neurology
  • Objective: To evaluate quantitative measures of eye movements as possible biomarkers in prediagnostic and early stages of Huntington disease (HD). Methods: The study sample (n = 215) included individuals both at risk and recently diagnosed with HD. All participants completed a uniform clinical evaluation which included administration of the Unified Huntington’s Disease Rating Scale (UHDRS) by a movement disorder neurologist and molecular testing to determine HD gene status. A high resolution… CONTINUE READING

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