Saccade dysmetria in head-unrestrained gaze shifts after muscimol inactivation of the caudal fastigial nucleus in the monkey.

@article{Quinet2005SaccadeDI,
  title={Saccade dysmetria in head-unrestrained gaze shifts after muscimol inactivation of the caudal fastigial nucleus in the monkey.},
  author={Julie Quinet and Laurent Goffart},
  journal={Journal of neurophysiology},
  year={2005},
  volume={93 4},
  pages={2343-9}
}
Lesions in the caudal fastigial nucleus (cFN) severely impair the accuracy of visually guided saccades in the head-restrained monkey. Is the saccade dysmetria a central perturbation in issuing commands for orienting gaze (eye in space) or is it a more peripheral impairment in generating oculomotor commands? This question was investigated in two head-unrestrained monkeys by analyzing the effect of inactivating one cFN on horizontal gaze shifts generated from a straight ahead fixation light… CONTINUE READING