Sa2050 Increased Gut Permeability in Patients With Metabolic Syndrome

  title={Sa2050 Increased Gut Permeability in Patients With Metabolic Syndrome},
  author={Vanessa Stadlbauer and Bettina Leber and Norbert Joachim Tripolt and Daniela Blattl and Martina Eder and Thomas R. Pieber and Th. Wascher and Rudolf E. Stauber and Karl Oettl and Harald Sourij},
Introduction: Obesity and metabolic disorders are linked to inflammation via gut flora and/ or gut permeability. Gut derived endotoxin triggers inflammation leading to metabolic syndrome (MetS) and contributing to oxidative stress. Aim: To investigate the effect of Lactobacillus casei Shirota on gut permeability, presence of endotoxin and neutrophil function in MetS. Patients and Methods: Patients with MetS were randomized to receive 3 x 6.5x109 CFU Lactobacillus casei Shirota (probiotic group… CONTINUE READING