SYNTHETIC STUDIES TOWARD HENNOXAZOLE A. USE OF A SELECTIVE BISOXAZOLE ALKYLATION AS THE KEY FRAGMENT COUPLING

@article{Smith2002SYNTHETICST,
  title={SYNTHETIC STUDIES TOWARD HENNOXAZOLE A. USE OF A SELECTIVE BISOXAZOLE ALKYLATION AS THE KEY FRAGMENT COUPLING},
  author={Thomas E. Smith and Emily P. Balskus},
  journal={Heterocycles},
  year={2002},
  volume={57},
  pages={1219-1225}
}
A model system for side chain fragment coupling to the core of hennoxazole A is investigated. Lateral metallation of a C 1 3 -TBS-protected bisoxazole, using lithium diethylamide, allows for selective and efficient alkylation at C 1 5 . 

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      SYNTHETIC STUDIES TOWARD HENNOXAZOLE A. USE OF A SELECTIVE BISOXAZOLE ALKYLATION AS THE KEY FRAGMENT COUPLING

      • 2002