SYNTHETIC STUDIES TOWARD HENNOXAZOLE A. USE OF A SELECTIVE BISOXAZOLE ALKYLATION AS THE KEY FRAGMENT COUPLING
@article{Smith2002SYNTHETICST, title={SYNTHETIC STUDIES TOWARD HENNOXAZOLE A. USE OF A SELECTIVE BISOXAZOLE ALKYLATION AS THE KEY FRAGMENT COUPLING}, author={Thomas E. Smith and Emily P. Balskus}, journal={Heterocycles}, year={2002}, volume={57}, pages={1219-1225} }
A model system for side chain fragment coupling to the core of hennoxazole A is investigated. Lateral metallation of a C 1 3 -TBS-protected bisoxazole, using lithium diethylamide, allows for selective and efficient alkylation at C 1 5 .
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SYNTHETIC STUDIES TOWARD HENNOXAZOLE A. USE OF A SELECTIVE BISOXAZOLE ALKYLATION AS THE KEY FRAGMENT COUPLING
- 2002