Corpus ID: 99278216

SYNTHESIS OF THIAZOLE SCAFFOLDS BY NOVEL METHOD AND THEIR IN VITRO ANTHELMINTIC ACTIVITY AGAINST INDIAN ADULT EARTHWORM

@inproceedings{Raut2015SYNTHESISOT,
  title={SYNTHESIS OF THIAZOLE SCAFFOLDS BY NOVEL METHOD AND THEIR IN VITRO ANTHELMINTIC ACTIVITY AGAINST INDIAN ADULT EARTHWORM},
  author={Dattatraya G. Raut and Vikas D. Kadu and Vikas D. Sonawane and R. Bhosale},
  year={2015}
}
A highly efficient and facile method has been described for the synthesis of substituted thiazoles and 2-aminothiazoles from phenacyl halide and thiourea in methanol using iodine as a catalyst at ambient temperature and product obtained in excellent yield within short time. The formation of these compounds was confirmed by IR, 1 H NMR, 13 C NMR and mass spectroscopy. The synthesized different substituted thiazoles (3a-3g) were taken for anthelmintic activity against Indian earthworm Pheretima… Expand
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