• Chemistry
  • Published 2012

SYNTHESIS OF CERTAIN COUMARINYL PYRAZOLINE - 5 - ONE DERIVATIVES AND EVALUA TION OF THEIR ANTIMICROBIAL, ANT IOXIDANT AND ANTI - TB ACTIVITIES

@inproceedings{Hariraj2012SYNTHESISOC,
  title={SYNTHESIS OF CERTAIN COUMARINYL PYRAZOLINE - 5 - ONE DERIVATIVES AND EVALUA TION OF THEIR ANTIMICROBIAL, ANT IOXIDANT AND ANTI - TB ACTIVITIES},
  author={N. Hariraj and Nagappan Kannappan},
  year={2012}
}
The aim of the present work was to synthesize certain coumarinyl pyrazoline - 5 - one derivatives and to eluc idate the potential role of these compounds as antimicrobial, antioxidant and anti - tubercular agents. The coumarinyl pyrazoline - 5 - one derivatives were prepared by condensing the unsaturated ester of diazotized Anilines with 6 - bromo substituted Coumarin - 3 - acid hydrazides. All the synthesized compounds showed promising anti - tube rcular activity against Mycobacterium… CONTINUE READING