SYNTHESIS, CHARACTERIZATION, QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP, DOCKING, ANTIBACTERIAL ACTIVITY, AND BRINE SHRIMP LETHAL STUDIES ON L-PHENYLALANINE SCHIFF BASES

@article{Deivanayagam2016SYNTHESISCQ,
  title={SYNTHESIS, CHARACTERIZATION, QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP, DOCKING, ANTIBACTERIAL ACTIVITY, AND BRINE SHRIMP LETHAL STUDIES ON L-PHENYLALANINE SCHIFF BASES},
  author={Easwaramoorthi Deivanayagam and R. Jayaprakash and Aroj Kumar Sha and S. Hemalatha},
  journal={Asian Journal of Pharmaceutical and Clinical Research},
  year={2016},
  volume={9},
  pages={203-208}
}
  • Easwaramoorthi Deivanayagam, R. Jayaprakash, +1 author S. Hemalatha
  • Published 2016
  • Biology
  • Asian Journal of Pharmaceutical and Clinical Research
  • ABSTRACT Objective: Aim of this work is to synthesize and characterization of the hydroxyl group the hydroxyl group substituted L-phenylalanine Schiff bases to compare their predicted quantitative structure-activity relationship (QSAR) and molecular docking against Escherichia coli protein ZipA (1s1j) outcomes with the antibacterial activity and brine shrimp lethal assay (BSLA) results. Methods: The Schiff bases of L-Phenylalanine were synthesized by the simple condensation reaction using… CONTINUE READING
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