SYNERGIC EFFECTS OF AMYLOBARBITONE SODIUM AND ETHANOL

@article{Fearn1953SYNERGICEO,
  title={SYNERGIC EFFECTS OF AMYLOBARBITONE SODIUM AND ETHANOL},
  author={H. J. Fearn and John R. Hodges},
  journal={Journal of Pharmacy and Pharmacology},
  year={1953},
  volume={5}
}
R ~ C ~ N T L Y , attention was drawn to the lack of information concerning the effects of ethanol and barbiturates taken t0gether.l In 1934, Carriere, Huriez and Willoquet2 reported that ethanol antagonised the hypnotic effect and reduced the toxicity of phenobarbitone. Several subsequent investigators have been unable to confirm this work. O l ~ z y c k a ~ ~ ~ found that ethanol potentiated the hypnotic effect of butobarbitone in mice and rats, and Dille and Ahlquist5, working on rabbits… Expand
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Summary1. The concentration of pentobarbitone in the liver, kidney, brain, muscle and blood of mice treated with ethanol is higher and declines more slowly than in controls.2. The concentration ofExpand
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