SWI/SNF and Asf1p cooperate to displace histones during induction of the saccharomyces cerevisiae HO promoter.
@article{Gkikopoulos2009SWISNFAA, title={SWI/SNF and Asf1p cooperate to displace histones during induction of the saccharomyces cerevisiae HO promoter.}, author={Triantafyllos Gkikopoulos and Kristina M Havas and Hilary Dewar and Tom Owen-Hughes}, journal={Molecular and cellular biology}, year={2009}, volume={29 15}, pages={ 4057-66 } }
Regulation of the Saccharomyces cerevisiae HO promoter has been shown to require the recruitment of chromatin-modifying and -remodeling enzymes. Despite this, relatively little is known about what changes to chromatin structure occur during the course of regulation at HO. Here, we used indirect end labeling in synchronized cultures to show that the chromatin structure is disrupted in a region that spans bp -600 to -1800 relative to the transcriptional start site. Across this region, there is a… CONTINUE READING
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