SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis


Actin plays a critical role during the early stages of pathogenic microbe internalization by immune cells. In this study, we identified a key mechanism of actin filament tethering and stabilization to the surface of phagosomes in human dendritic cells. We found that the actin-binding protein SWAP70 is specifically recruited to nascent phagosomes by binding… (More)
DOI: 10.1016/j.celrep.2016.10.021