SWAP-70 associates transiently with macropinosomes.

  title={SWAP-70 associates transiently with macropinosomes.},
  author={Pia Oberbanscheidt and Sandra Balkow and Jochen Kuehnl and Stephan Grabbe and Martin B{\"a}hler},
  journal={European journal of cell biology},
  volume={86 1},
Cells accomplish the non-selective uptake of extracellular fluids, antigens and pathogens by the endocytic process of macropinocytosis. The protein SWAP-70 is a widely expressed, pleckstrin-homology (PH) domain-containing protein that marks a transitional subset of actin filaments in motile cells. Here we report that the protein SWAP-70 associates transiently with macropinosomes in dendritic cells and NIH/3T3 fibroblasts. The association of SWAP-70 with macropinosomes is preceded by the… CONTINUE READING

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