SVCT1 and SVCT2: key proteins for vitamin C uptake

Abstract

Vitamin C is accumulated in mammalian cells by two types of proteins: sodium-ascorbate co-transporters (SVCTs) and hexose transporters (GLUTs); in particular, SVCTs actively import ascorbate, the reduced form of this vitamin. SVCTs are surface glycoproteins encoded by two different genes, very similar in structure. They show distinct tissue distribution and… (More)
DOI: 10.1007/s00726-007-0555-7

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