SUPPRESSION OF BREAST CANCER CELL GROWTH WITH GRAPE JUICE

@article{Chen1998SUPPRESSIONOB,
  title={SUPPRESSION OF BREAST CANCER CELL GROWTH WITH GRAPE JUICE},
  author={Shiuan Chen and Xiuying Sun and Y. Kao and A. Kwon and Dujin Zhou and E. Eng},
  journal={Pharmaceutical Biology},
  year={1998},
  volume={36},
  pages={53-61}
}
Aromatase (CYP19) converts androgens to estrogens. By synthesizing estrogens, aromatase (especially tumor aromatase) is thought to play an important role in promoting breast cancer growth in postmenopausal women. By inhibiting estrogen biosynthesis, aromatase inhibitors, including phytochemicals, are potential chemopreventive agents for breast cancer. Our recent aromatase inhibition experiments have revealed that grape juice contains compounds that inhibit aromatase. Inhibition kinetic analysis… Expand

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