SUMO wrestling with type 1 diabetes

@article{Li2005SUMOWW,
  title={SUMO wrestling with type 1 diabetes},
  author={Manyu Li and Dehuang Guo and Carlos M. Isales and D{\'e}cio L. Eizirik and Mark A. Atkinson and Jin-Xiong She and Cong‐Yi Wang},
  journal={Journal of Molecular Medicine},
  year={2005},
  volume={83},
  pages={504-513}
}
Post-translational modification of proteins by phosphorylation, methylation, acetylation, or ubiquitylation represent central mechanisms through which various biological processes are regulated. Reversible covalent modification (i.e., sumoylation) of proteins by the small ubiquitin-like modifier (SUMO) has also emerged as an important mechanism contributing to the dynamic regulation of protein function. Sumoylation has been linked to the pathogenesis of a variety of disorders including… 
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