SUMO: a (Oxidative) Stressed Protein

@article{Feligioni2013SUMOA,
  title={SUMO: a (Oxidative) Stressed Protein},
  author={Marco Feligioni and Robert Nistic{\`o}},
  journal={NeuroMolecular Medicine},
  year={2013},
  volume={15},
  pages={707-719}
}
Redox species are produced during the physiological cellular metabolism of a normal tissue. In turn, their presence is also attributed to pathological conditions including neurodegenerative diseases. Many are the molecular changes that occur during the unbalance of the redox homeostasis. Interestingly, posttranslational protein modifications (PTMs) play a remarkable role. In fact, several target proteins are modified in their activation, localization, aggregation, and expression after the… CONTINUE READING
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