SULT1A1 genotype and susceptibility to colorectal cancer.

@article{Lilla2007SULT1A1GA,
  title={SULT1A1 genotype and susceptibility to colorectal cancer.},
  author={Carmen Lilla and Angela Risch and Emaculate Verla-Tebit and Michael Hoffmeister and Hermann Brenner and Jenny Chang-Claude},
  journal={International journal of cancer},
  year={2007},
  volume={120 1},
  pages={
          201-6
        }
}
Several procarcinogens that are present in cooked red meat and tobacco smoke are substrates for sulfotransferase 1A1 (SULT1A1). The association between environmental exposures and colorectal cancer risk may be modified by individual differences in the metabolism. Thus, we investigated the effect of a common polymorphism in the SULT1A1 gene associated with decreased enzyme activity on the susceptibility to colorectal cancer in a population-based case-control study. Patients (505) and 604 age… CONTINUE READING
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Sulfotransferase genetic variation: from cancer risk to treatment response.

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Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk.

  • Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
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