STUDY ON THE CORRELATION BETWEEN THE EXPRESSION OF p53 AND MDR IN LUNG CANCER

@inproceedings{Yan2002STUDYOT,
  title={STUDY ON THE CORRELATION BETWEEN THE EXPRESSION OF p53 AND MDR IN LUNG CANCER},
  author={Wang Yan},
  year={2002}
}
Objective:To investigate the correlation between p53 protein and multidrug resistance in lung cancer.Methods:The expression of p53 protein was examined by means of SP immunohistochemical technique,mdr 1 and mrp gene expression was determined by RT PCR method in 40 cases of lung cancer tissues proved by pathology and normal lung tissues of adjacent tumor.The relationship between the expression of p53 protein and mdr 1,mrp gene was analyzed respectively.Results:The positive incidence of mutant… CONTINUE READING