STUDIES ON THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE. I. ENZYMIC SYNTHESIS OF NIACIN RIBONUCLEOTIDES FROM 3-HYDROXYANTHRANILIC ACID IN MAMMALIAN TISSUES.

@article{Nishizuka1963STUDIESOT,
  title={STUDIES ON THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE. I. ENZYMIC SYNTHESIS OF NIACIN RIBONUCLEOTIDES FROM 3-HYDROXYANTHRANILIC ACID IN MAMMALIAN TISSUES.},
  author={Y. Nishizuka and O. Hayaishi},
  journal={The Journal of biological chemistry},
  year={1963},
  volume={238},
  pages={
          3369-77
        }
}
  • Y. Nishizuka, O. Hayaishi
  • Published 1963
  • Medicine, Biology
  • The Journal of biological chemistry
  • In 1956, McDaniel, Hundley, and Sebrell (1) reported that urinary excretion of N’n~ethylnicotinamide decreased in alloxan-diabetic rats. Mehler, McDaniel, and Hundley (2) subsequently showed that the level of liver picolinic carboxylase increased markedly in alloxan-diabetic rats and was inversely related with urinary excretion of N’-methylnicotinamide. Previous nutritional studies have indicated that capacity of converting tryptophan to niacin varies with species of animals (3, 4). Cats… CONTINUE READING
    160 Citations
    Studies on the biosynthesis of nicotinamide-adenine dinucleotide in the brain.
    • 69

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