• Chemistry, Medicine
  • Published in
    The journal of histochemistry…
    1971
  • DOI:10.1177/19.6.382

STUDIES IN MYOCLONUS EPILEPSY III. THE EFFECTS OF AMYLOLYTIC ENZYMES ON THE ULTRASTRUCTURE OF LAFORA BODIES

@article{Nikaido1971STUDIESIM,
  title={STUDIES IN MYOCLONUS EPILEPSY III. THE EFFECTS OF AMYLOLYTIC ENZYMES ON THE ULTRASTRUCTURE OF LAFORA BODIES},
  author={Tamotsu Nikaido and J. Austin and Hans Stukenbrok},
  journal={Journal of Histochemistry and Cytochemistry},
  year={1971},
  volume={19},
  pages={382 - 385}
}
Sections containing Lafora bodies were exposed to the action of amylolytic enzymes. These enzymes split the glucose linkages of glucose polymers (polyglucosans). The following ultrastructural changes were observed: (a) the fibrils of Lafora bodies were greatly reduced in number; (b) the staining intensity of the fibrils was reduced; (c) the amorphous densities were no longer seen. The evidence suggests that the fibrils and amorphous densities of Lafora bodies are both polyglucosan in nature… CONTINUE READING

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