STREPTOCOCCAL M ANTIGEN LOCATION AND SYNTHESIS, STUDIED BY IMMUNOFLUORESCENCE

@article{Hahn1963STREPTOCOCCALMA,
  title={STREPTOCOCCAL M ANTIGEN LOCATION AND SYNTHESIS, STUDIED BY IMMUNOFLUORESCENCE},
  author={Jerome J. Hahn and Roger M. Cole},
  journal={The Journal of Experimental Medicine},
  year={1963},
  volume={118},
  pages={659 - 666}
}
Streptococcal M protein has been studied directly in the intact streptococcal cell by specific immunofluorescence. By this method, it can be seen to be concentrated in or on the cell wall, but cannot be detected in the capsule. The lack of type-specific (but not group-specific) immunofluorescence after trypsinization; and the inhibition of group-specific immunofluorescence by unlabeled type-specific antibody, are observations most compatible with a location of the M antigen determinants on the… CONTINUE READING

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