STRAD pseudokinases regulate axogenesis and LKB1 stability

Abstract

Neuronal polarization is an essential step of morphogenesis and connectivity in the developing brain. The serine/threonine kinase LKB1 is a key regulator of cell polarity, metabolism, tumorigenesis, and is required for axon formation. It is allosterically regulated by two related and evolutionarily conserved pseudokinases, STe20-Related ADapters (STRADs… (More)
DOI: 10.1186/1749-8104-9-5

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@inproceedings{VelevaRotse2013STRADPR, title={STRAD pseudokinases regulate axogenesis and LKB1 stability}, author={Biliana O. Veleva-Rotse and James L. Smart and Annette F. Baas and Benjamin Edmonds and Zi-ming Zhao and Allyson J Brown and Lillian R. Klug and Kelly D Hansen and Gabrielle Reilly and Alexandria P Gardner and Krishnaveni Subbiah and Eric A. Gaucher and Hans Clevers and Anthony P. Barnes}, booktitle={Neural Development}, year={2013} }