STING-dependent cytosolic DNA sensing pathways.


STING (STimulator of INterferon Genes) has recently been identified as being essential for controlling host defense countermeasures triggered by microbial cytosolic DNA and subsequently cyclic dinucleotides (CDNs). However, chronic STING activation may also be responsible for initiating certain inflammatory diseases manifested by self DNA. Recent studies… (More)
DOI: 10.1016/


Cite this paper

@article{Barber2014STINGdependentCD, title={STING-dependent cytosolic DNA sensing pathways.}, author={Glen N Barber}, journal={Trends in immunology}, year={2014}, volume={35 2}, pages={88-93} }