STIM1 Regulates Platelet-Derived Growth Factor-Induced Migration and Ca2+ Influx in Human Airway Smooth Muscle Cells

Abstract

It is suggested that migration of airway smooth muscle (ASM) cells plays an important role in the pathogenesis of airway remodeling in asthma. Increases in intracellular Ca(2+) concentrations ([Ca(2+)](i)) regulate most ASM cell functions related to asthma, such as contraction and proliferation. Recently, STIM1 was identified as a sarcoplasmic reticulum (SR… (More)
DOI: 10.1371/journal.pone.0045056

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@inproceedings{Suganuma2012STIM1RP, title={STIM1 Regulates Platelet-Derived Growth Factor-Induced Migration and Ca2+ Influx in Human Airway Smooth Muscle Cells}, author={Nobukazu Suganuma and Satoru Ito and Hiromichi Aso and Masashi Kondo and Mitsuo Sato and Masahiro Sokabe and Yoshinori Hasegawa}, booktitle={PloS one}, year={2012} }