STEPS: efficient simulation of stochastic reaction–diffusion models in realistic morphologies

@inproceedings{Hepburn2011STEPSES,
  title={STEPS: efficient simulation of stochastic reaction–diffusion models in realistic morphologies},
  author={Iain Hepburn and Weiliang Chen and Stefan Wils and Erik De Schutter},
  booktitle={BMC Systems Biology},
  year={2011}
}
Models of cellular molecular systems are built from components such as biochemical reactions (including interactions between ligands and membrane-bound proteins), conformational changes and active and passive transport. A discrete, stochastic description of the kinetics is often essential to capture the behavior of the system accurately. Where spatial effects play a prominent role the complex morphology of cells may have to be represented, along with aspects such as chemical localization and… CONTINUE READING
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