STEAP4, a gene associated with insulin sensitivity, is regulated by several adipokines in human adipocytes.

  title={STEAP4, a gene associated with insulin sensitivity, is regulated by several adipokines in human adipocytes.},
  author={X. Chen and Chun Zhu and Chen-bo Ji and Y. Zhao and C. Zhang and Fukun Chen and Chunlin Gao and Jingai Zhu and L. Qian and X. Guo},
  journal={International journal of molecular medicine},
  volume={25 3},
  • X. Chen, Chun Zhu, +7 authors X. Guo
  • Published 2010
  • Biology, Medicine
  • International journal of molecular medicine
  • We previously identified a six-transmembrane epithelial antigen of the prostate (STEAP) 4 as a novel plasma membrane protein that is downregulated in obese patients and may play a significant role in the development of human obesity. This study was designed to identify the biological characteristics of the STEAP4 gene in human adipocytes. On the basis of oil red O staining and the expression profiles of specific markers, we demonstrated that overexpression of STEAP4 did not affect adipogenesis… CONTINUE READING
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