STEAP4, a gene associated with insulin sensitivity, is regulated by several adipokines in human adipocytes.

@article{Chen2010STEAP4AG,
  title={STEAP4, a gene associated with insulin sensitivity, is regulated by several adipokines in human adipocytes.},
  author={Xiaohui Chen and Chun Zhu and Chen-bo Ji and Yaping Zhao and Chunmei Zhang and Fukun Chen and Chunlin Gao and Jingai Zhu and Lingmei Qian and Xi-rong Guo},
  journal={International journal of molecular medicine},
  year={2010},
  volume={25 3},
  pages={
          361-7
        }
}
We previously identified a six-transmembrane epithelial antigen of the prostate (STEAP) 4 as a novel plasma membrane protein that is downregulated in obese patients and may play a significant role in the development of human obesity. This study was designed to identify the biological characteristics of the STEAP4 gene in human adipocytes. On the basis of oil red O staining and the expression profiles of specific markers, we demonstrated that overexpression of STEAP4 did not affect adipogenesis… CONTINUE READING

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