STATISTICAL METHODS IN BIOLOGY

@article{ZhangSTATISTICALMI,
  title={STATISTICAL METHODS IN BIOLOGY},
  author={Lingsong Zhang},
  journal={The Ulster Medical Journal},
  volume={50},
  pages={140 - 140}
}
THE third part of Biometrika, published in April, contains several important contributions, the first of which is by Prof. Karl Pearson, who describes “a systematic method of curve-fitting by moments.” For practical purposes it is found that if good quadrature formulæ are used this method is as good as the well-known method of least squares, and in some cases is applicable where the older method fails. Examples of the application of the new method are given. A communication on the sources of… 
EFFECTIVE POPULATION NUMBERS IN THE SNAIL CEPAEA NEMORALIS
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  • 1974
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It is shown that the size of an ideal population that would have the same sampling variance or rate of inbreeding as the observed population and the effective population number may not be identical.
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The foundations of biometrical genetics were first laid in a famous paper by R. A. Fisher [1]. Since that time a considerable amount of literature has accumulated, the book by Mather and Jinks [2]
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The type 1 error rate of the Mann–Whitney U test inflates under unequal variance (heteroscedasticity) and some solutions are suggested.
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A new method for calculating the accretion rate (A) of bone calcium is proposed, based on an impulse analysis of47Ca data, free of most of the assumptions inherent in previous methods of analysis and appears to give more accurate estimates.
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Phenylbutazone metabolism in man is shown to be under polygenic control, and genetically controlled in a similar manner and to a similar degree to body height, which may lead to improved therapeutic efficacy and a lower incidence of adverse reactions.
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The mathematical and computational analysis in Cavalli-Sforza and Feldman (1973) showed that the direct phenotypic transmission from parents to children could produce the appearance of high heritability even though the transmission was not genetic.
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